Top 5 Supplements & Vitamins from Nature Made to Support a Healthy Mood†

May 05, 2023 Mood 5 MIN

Top 5 Supplements & Vitamins from Nature Made to Support a Healthy Mood†

Quick Health Scoop

  • Your nutrition plays a large role in supporting a healthy mood.
  • Getting in the right vitamins and supplements can support l mood health.
  • You can support a happier you with a combination of a healthy diet and mood-supporting supplements.

 Are you looking to support your emotional well-being? If so, look no further than good nutrition! By prioritizing the best vitamins to support healthy mood, you’ll say hello to a brighter, happier you.

As a registered dietitian, I always emphasize the importance of a balanced, nutritious diet. But I also know it’s not always possible to eat healthily and get in everything you need from your food. In these cases, taking a quality supplement can support a healthy mood.

Here we’ll unpack the top 5 vitamins and supplements for mood, share the science, and the benefits of Nature Made’s® mood-supporting supplements.

What Are Mood Supporting Supplements?

In addition to following a healthy diet and lifestyle, incorporating mood-supporting supplements can support overall emotional well-being. These supplements work by supporting the normal function of various neurotransmitters, hormones, and other chemicals in the brain for a healthy mood.

The Types of Supplements

Several supplements can help support a positive mood such as B-complex vitamins and other amino acids and compounds such as 5-HTP and SAM-e. Before starting a supplement regimen for mood, speak to your healthcare provider to determine the best plan for you.

Ways to Balance Mood

While several vitamins and supplements for mood can support emotional well-being, there are additional ways to balance your mood that you can incorporate into your daily life. These include:

  • Prioritizing good nutrition - Eating a well-balanced diet with plenty of nutrient-rich fruit, vegetables, and whole grains.
  • Exercising regularly - This can be exercise in any way, shape, or form. The most important thing is to move your body in a way that feels good to you (and that you look forward to!).
  • Being social - Staying connected with loved ones and friends regularly is a proven way to boost your mood.
  • Getting proper sleep - Getting at least 7-8 hours of quality shut-eye equals a healthier, happier you.
  • Being outside in nature - Getting fresh air (even if it’s cold air) on the regular has a big impact on your happy hormones. Even just getting outside for 5 minutes a day works wonders!

Learn more: Ways to Support A Healthy Mood

What Nutrients Can Help Balance Mood?

While good nutrition overall can support a healthy mood, there are a few specific vitamins for mood to put on the top of your list.

1.   Vitamin B6

Vitamin B6 is one of 8 B-complex vitamins that support a healthy brain and cellular energy metabolism. It supports the production of neurotransmitters (i.e. chemical messengers) as well as SAM-E (S-adenosylmethionine), all needed for mood health.[1] Getting enough Vitamin B6 can help you get ready for the day!

Vitamin B6 is found in beef liver, tuna, salmon, poultry, fortified cereals, and chickpeas. You can also consider a B-complex vitamin or Multivitamin containing Vitamin B6 if you aren’t getting enough of these foods in your diet.

2.   Folic Acid

Also known as Vitamin B9, Folic acid is another B vitamin that supports a healthy mood. Similar to B6, it helps support the production of neurotransmitters and SAM-e which are important to mental function and mood health.[2]

Folic Acid is found in dark leafy green vegetables, beans, peanuts, sunflower seeds, and whole grains. You can also take a B-complex or Multivitamin for added peace of mind.

3.   Vitamin B12

Vitamin B12 is another vitamin in the B-complex family linked to brain health and mood through its role in supporting the production of neurotransmitters needed for mood health.[3]

Vitamin B12 is found in several foods, but mainly in animal sources including meat, fish, poultry, eggs, and dairy. Therefore if you are a vegetarian or don’t eat meat regularly, it may be challenging to get in enough Vitamin B12 in your diet alone.

If you’re concerned you may not be getting enough Vitamin B12, ask your doctor for supplement recommendations.

4.   5-HTP

Known as 5-Hydroxytryptophan, 5-HTP is an amino acid (protein-building block)  produced by the body that helps support mood health. It plays a role in emotional well-being by providing nutritional support to neurotransmitter production such as serotonin.

Nature Made® 5-HTP Chewable Tablets and Nature Made® Wellblends Positive Mood & Energy™ Softgels both provide 5-HTPwhich helps make serotonin to support a positive mood.

Learn More: What are the Benefits of 5-HTP?

5.   SAM-e

Sometimes your emotions may be out of balance, causing you to feel moody. This imbalance can be associated with low levels of SAM-e, a compound made  by the body important for neurotransmitter production and mood health.[4]

In the brain, SAM-e helps produce the neurotransmitter serotonin, but levels can run low due to various factors such as diet and aging. Nature Made® SAM-e Complete®♦ 400 mg tablets can support a healthy mood and emotional well-being.

Learn more: A Guide To The B Vitamins

Benefits of Nature Made’s Mood-Supporting Supplements

Clinically Studied SAM-e

Our Nature Made mood-supporting supplement  SAM-e has been clinically studied to support a healthy mood.

For example, you can replenish your SAM-e levels and feel the difference in as little as 7-14 days when taken daily. You can do this easily with our Nature Made® SAM-e Complete®♦ 400 mg tablets.

If you are looking for an alternative to SAM-e, consider our Nature Made® 5-HTP Chewable Tablets and Nature Made® Wellblends Positive Mood & Energy™ both contain at least the 50 mg dose of 5-HTP which helps make serotonin  to support a positive mood.

Superior Quality

We are the #1 pharmacist recommended vitamin and supplement brand* .

Supporting your mood and emotional well-being is an essential aspect of leading a healthy, fulfilling life. By incorporating the 5 top vitamins for mood we discussed here, you can support your goal of becoming a healthier, happier you.

One of the easiest ways to get in your daily dose of these vitamins for mood is to take a mood-supporting supplement, such as Nature Made® Wellblends Positive Mood & Energy™.

Speak to your doctor about your options and how you can use the power of nutrition to support a healthy mood.

Learn More About Mood-Supporting Nutrients

Follow @NatureMadeVitamins on Instagram for new product news, healthy tips, and more.

* Based on a survey of pharmacists who recommend branded vitamins and supplements.

♦Complete because studies have shown that SAM-e helps support a healthy mood and joint comfort.

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.


  1. Vitamin B6. Fact Sheet for Health Professionals. National Institutes of Health - Office of Dietary Supplements. Accessed on April 12, 2023:
  2. Folic Acid. Fact Sheet for Health Professionals. National Institutes of Health - Office of Dietary Supplements. Accessed on April 12, 2023:
  3. Vitamin B12. Fact Sheet for Health Professionals. National Institutes of Health - Office of Dietary Supplements. Accessed on April 12, 2023:
  4. Mount Sinai Health Library. S-adenosylmethionine. Icahn School of Medicine at Mount Sinai. Accessed on April 12, 2023:


Melissa Mitri, MS, RD

NatureMade Contributor

Melissa Mitri, RD is a seasoned dietitian and health writer. She specializes in helping women move away from restrictive habits that lead to vicious yo-yo weight cycles. Melissa enjoys writing about health, nutrition, and fitness with the goal of simplifying complex health topics for the reader. Find out more about Melissa at

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Lynn M. Laboranti, RD

Science and Health Educator

Lynn is a Registered Dietitian (R.D.) and is a member of the Medical and Scientific Communications team at Pharmavite. She has over 20 years of experience in integrative and functional nutrition and has given lectures to health professionals and consumers on nutrition, dietary supplements and related health issues. Lynn frequently conducts employee trainings on various nutrition topics in addition to educating retail partners on vitamins, minerals and supplements. Lynn has previous clinical dietitian expertise in both acute and long-term care, as well as nutrition counseling for weight management, diabetes, and sports nutrition. Lynn earned a bachelor’s of science in Nutrition with a minor in Kinesiology/Exercise Science from The Pennsylvania State University. She earned a M.S. degree in Human Nutrition from Marywood University in Scranton, Pennsylvania. Lynn is an active member of the Academy of Nutrition and Dietetics, Sports Cardiovascular and Wellness Nutritionists, Dietitians in Functional Medicine, and holds a certification in Integrative and Functional Nutrition through the Academy of Nutrition and Dietetics.

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