How long will SAM-e take to work?

Many people report mood improvement in as little as one to two weeks. If after 2 weeks you are not experiencing desired benefits, you may want to try gradually increasing the dose after consulting with your doctor. If you're taking SAM-e for your joints, you may have to wait up to a month to experience results.

How long should I keep taking SAM-e?

SAM-e supplements may be taken on a daily basis. SAM-e can be used daily to benefit mood and support joint health. So you can continue taking SAM-e as long as you are not experiencing any adverse effects and experience results. If you have any concerns or have changes in your medications, please consult your doctor.†

Why Do I Want Subscribe & Save?

It's Easy & Flexible Set it and forget it. You can change, pause, and cancel anytime. Membership Exclusive Get 10% discount on every order plus free shipping**. Learn More **When you purchase one or more products on subscription, you will automatically get free shipping on this and all future deliveries. Offer excludes tax and is subject to change. Orders outside of the contiguous US, including Alaska & Hawaii will be charged $8 for shipping.

When does this product expire?

Please refer to the expiration date on the bottle.

SAM-e Complete 400 mg | Restore Healthy Mood

Name: SAM-e Complete®◆ 400 mg Tablets
Brand: Nature Made
SKU: 1107ZS
Price: 62.19 USD
Availability: InStock

A healthy mood sets the tone for your whole day. SAM-e is a molecule made in the cells of our bodies. However, SAM-e levels can run low due to various factors such as diet and aging. Nature Made® SAM-e Complete®◆ can help to replenish your SAM-e levels and restore your healthy mood in as little as 7–14 days when taken daily. Nature Made® SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue. It's now that much easier to stay on top of your health.†

Provides 400 mg of SAM-e per tablet
Clinically studied to help support a healthy mood†
Help restore a healthy mood in as little as 7-14 days when taken daily†
Helps support joint comfort†

Supports

MOOD
JOINTS

Product Facts

SOURCED FROM HIGH QUALITY INGREDIENTS
CAN BE FOUND IN RED MEAT

What's in our SAM-e Complete®◆ 400 mg Tablets

Ingredients

Amount Per Serving: SAM-e 400mg

No Artificial Flavors
No Preservatives
Gluten Free

What dietary shortfalls does this product address?

SAM-e is made in most cells of the body and there are no direct SAM-e dietary sources.

Where do we normally get this product from?

Increasing your intake of foods containing the amino acid methionine may help your body increase its SAM-e production. Methionine food sources include protein foods such as fish, beef, eggs and chicken as well as nuts and seeds.

Who might need to take this product?

Glad you asked. SAM-e levels can run low due to various factors such as diet and aging.

Suggested Use: Start with 1 tablet per day. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. Clinical studies indicate that benefits are most likely evident after 7–14 days of supplementation.^† If benefits are not achieved within two weeks, you may require a higher level of supplementation. To help determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1,600 mg/day) and consult with your doctor until benefits are achieved.

Interactions

People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision. If you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before using this product. Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a healthcare professional before using this product.

Use Caution:

People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide should not take this or any other product containing SAM-e except under a doctor's supervision. If you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before using this product. SAM-e should be avoided when taking: St. John’s Wort and MAO Inhibitors, like Marplan, Nardil, Parnate and Manerix. SAM-e should be used with caution and only under a doctor’s supervision when combined with other drugs that increase neurotransmitters in the body, such as Selective Serotonin Reuptake Inhibitors (SSRIs).

Disclaimer:

*Based on U.S. News & World Report - Pharmacy Times Survey of pharmacists recommending this category.

‡Provides SAM-e which is produced and used by the body.

♦Complete because studies have shown that SAM-e helps support a healthy mood and joint comfort.†

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Benefits & Description
A healthy mood sets the tone for your whole day. SAM-e is a molecule made in the cells of our bodies. However, SAM-e levels can run low due to various factors such as diet and aging. Nature Made® SAM-e Complete®◆ can help to replenish your SAM-e levels and restore your healthy mood in as little as 7–14 days when taken daily. Nature Made® SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue. It's now that much easier to stay on top of your health.†
Provides 400 mg of SAM-e per tablet
Clinically studied to help support a healthy mood†
Help restore a healthy mood in as little as 7-14 days when taken daily†
Helps support joint comfort†
Supports

MOOD

JOINTS
Product Facts

SOURCED FROM HIGH QUALITY INGREDIENTS

CAN BE FOUND IN RED MEAT
Ingredients
What's in our SAM-e Complete®◆ 400 mg Tablets
Ingredients

Amount Per Serving: SAM-e 400mg
- No Artificial Flavors
- No Preservatives
- Gluten Free
More Information
Nutrient Shortfalls

What dietary shortfalls does this product address?

SAM-e is made in most cells of the body and there are no direct SAM-e dietary sources.

Where do we normally get this product from?

Increasing your intake of foods containing the amino acid methionine may help your body increase its SAM-e production. Methionine food sources include protein foods such as fish, beef, eggs and chicken as well as nuts and seeds.

Who might need to take this product?

Glad you asked. SAM-e levels can run low due to various factors such as diet and aging.
Dosage & Interactions
Suggested Use: Start with 1 tablet per day. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. Clinical studies indicate that benefits are most likely evident after 7–14 days of supplementation.^† If benefits are not achieved within two weeks, you may require a higher level of supplementation. To help determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1,600 mg/day) and consult with your doctor until benefits are achieved.

Interactions

People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision. If you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before using this product. Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a healthcare professional before using this product.
Use Caution:

People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide should not take this or any other product containing SAM-e except under a doctor's supervision. If you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before using this product. SAM-e should be avoided when taking: St. John’s Wort and MAO Inhibitors, like Marplan, Nardil, Parnate and Manerix. SAM-e should be used with caution and only under a doctor’s supervision when combined with other drugs that increase neurotransmitters in the body, such as Selective Serotonin Reuptake Inhibitors (SSRIs).

Disclaimer:

*Based on U.S. News & World Report - Pharmacy Times Survey of pharmacists recommending this category.

‡Provides SAM-e which is produced and used by the body.

♦Complete because studies have shown that SAM-e helps support a healthy mood and joint comfort.†

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

SAM-e Complete®◆ 400 mg Tablets

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"I love that this takes care of my mood and joints as well. Although I'm still relatively young, I'd like to start taking care of my joints early. Good mood is an added bonus."

Verified Purchaser

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Questions? VIEW ALL FAQ VIEW ALL FAQ on Questions?

See our frequently asked questions below:

Why take SAM-e?

Nature Made^® SAM-e Complete^®◆ products help support a healthy mood as well as joint comfort, which may naturally deteriorate with physical activity and age. SAM-e also provides a source of sulfur—an essential component of joint tissue.^†
How much SAM-e should I take daily?

You should start out with 400 mg of SAM-e every day. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1,600 mg/day) and consult with your doctor until you begin to experience the desired benefits.
How long will SAM-e take to work?

Many people report mood improvement in as little as one to two weeks. If after 2 weeks you are not experiencing desired benefits, you may want to try gradually increasing the dose after consulting with your doctor. If you're taking SAM-e for your joints, you may have to wait up to a month to experience results.
How long should I keep taking SAM-e?

SAM-e supplements may be taken on a daily basis. SAM-e can be used daily to benefit mood and support joint health. So you can continue taking SAM-e as long as you are not experiencing any adverse effects and experience results. If you have any concerns or have changes in your medications, please consult your doctor.^†
Why Do I Want Subscribe & Save?

It's Easy & Flexible

Set it and forget it. You can change, pause, and cancel anytime.

Membership Exclusive

Get 10% discount on every order plus free shipping**.

Learn More

**When you purchase one or more products on subscription, you will automatically get free shipping on this and all future deliveries. Offer excludes tax and is subject to change. Orders outside of the contiguous US, including Alaska & Hawaii will be charged $8 for shipping.
When does this product expire?

Please refer to the expiration date on the bottle.

VIEW ALL FAQ

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SAM-e Complete^®◆ 400 mg Tablets