Studies Using Nature Made

Pharmavite (the makers of NatureMade), has been a trusted leader in health and wellness with over 50 years of commitment to research, science and innovation. The quality of our products is recognized by the scientific community as our products have been used in over 140 clinical studies. We are a go-to source for nutrition supplement intervention studies, providing product and placebo for clinical trials around the globe. Pharmavite has collaborated with over 55 leading health and science institutions to donate product for over 90 studies, including the recent VITAL study.

From a substantial total list, we are pleased to share links to a few of the most well-known studies that used Nature Made products:


• Determination of coenzyme Q10 content in raw materials and dietary supplements by high-performance liquid chromatography-UV: collaborative study. (Lunetta, Roman; 2008; Ten collaborating labs)
Key finding: HPLC-UV testing is effective and dependable for CoQ10


• Effects of short-term folic acid and/or riboflavin supplementation on serum folate and plasma total homocysteine concentrations in young Japanese male subjects. (Araki, et al. 2006; Japan Women’s University)
Key finding: Serum folate concentrations increased in folic acid groups


• Premenopausal overweight women do not lose bone during moderate weight loss with adequate or higher calcium intake. (Riedt, et al; 2006; Rutgers University)
Key finding: Bone mass was maintained with calcium supplementation


• Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation. (Bruno, et al. 2005; Linus Pauling Institute at Oregon State University)
Key finding: Vitamin C recycles Vitamin E


• S-Adenosyl-L-Methionine (SAMe) as an Adjunct for Resistant Major Depressive Disorder: An Open Trial Following Partial or Nonresponse to Selective Serotonin Reuptake Inhibitors or Venlafaxine. (Alpert, et al. 2004)
Key finding: Potential of SAM-e as treatment approach (small sample size)


• Vitamin E treatment of nonalcoholic steatohepatitis (NASH) in children: A pilot study. (J. Lavine. 2000)
Key finding: Vitamin E potential treatment for NASH