Science Based

Scientific research is the starting point for everything we do! Our team of scientists evaluates each Nature Made® product to ensure that the science shows it to be safe and that it provides a benefit to our consumers.

We strive to set an example of how dietary supplement companies should approach developing and manufacturing new and innovative products. So, we perfected a three-pronged approach to how we evaluate and substantiate the scientific basis for our products:

Review of Scientific Literature

We constantly track emerging science on nutrition, but we do not chase fads. On staff, we have PhDs and Registered Dietitians who lead health and nutrition discussions within our company. Through this review process, we often choose to develop products with evidence-based scientific support and discard product ideas, even popular ones, if they lack sufficient benefit or safety evidence. 

Support for Public Studies

We strongly believe that vitamins and supplements deserve more independent academic and institutional research. We are proud that Nature Made® supplements are sought out for clinical research studies by the leading science and health institutions because they can count on our product quality and consistency. In the last 20 years, Nature Made® products have been utilized or cited in numerous clinical studies.

Product-Specific Clinical Trials

We design and implement clinical studies for certain Nature Made® products to measure the benefit provided by our unique ingredients or blends. For example, we clinically tested our CholestOff™ products and found it provided clear efficacy for lowering dietary cholesterol levels.‡ We intend to continue this path of specific clinical studies for select Nature Made® products in the future.

Beyond our products, we are committed to advancing Evidenced-Based Nutrition (EBN) science—an inclusive research model that considers the totality of all available evidence. Our experts work closely with researchers and healthcare professionals to better understand the human body and supports people’s health.



‡Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of Nature Made CholestOff Original® supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.