• Nature Made SAM-e Complete 200 mg
  • Nature Made SAM-e Complete 200 mg

SAM-e Complete 200 mg

Tablets

Nature Made SAM-e Complete can help replenish your SAM-e level and restore a healthy mood.

  • Clinically studied to help restore a healthy mood in as little as 7 to 14 days when taken daily
  • #1 Best Selling Brand of SAM-e supplement*
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Product Details

Maintaining your SAM-e levels plays an important role in supporting a healthy mood. SAM-e is a naturally occurring molecule made in the cells of our body. However, SAM-e levels can run low due to various factors such as diet and aging. Nature Made SAM-e Complete can help to replenish your SAM-e levels and restore your healthy mood when taken daily. If you are new to SAM-e, Nature Made SAM-e Complete 200 mg is a great place to start.

Nature Made SAM-e also helps support joint comfort, which may naturally deteriorate with physical activity and age. SAM-e provides a source of sulfur, which is a critical component of joint tissue.

  • #1 Best Selling Brand of SAM-e supplement*
  • Clinically studied to help support a healthy mood
  • Help restore a healthy mood in as little as 7 to 14 days when taken daily
  • 100% money back guarantee**

Nature Made SAM-e Complete is made to Nature Made’s guaranteed purity and potency standards.

  • No Artificial Flavors
  • No Preservatives
  • No Yeast
  • Gluten Free

Available Sizes: 24 Count / 60 Count

*# 1 Brand of SAM-e supplements based on POS scan data at Food, Drug, Mass and Club

**Visit NatureMade.com/guarantee for details.

Dosage and Interactions

When to Take:

Start with 2 tablets per day. The best time to take SAM-e is on an empty stomach at least 30 minutes before a meal. Clinical studies indicate that benefits are most likely evident in as little as 7-14 days of supplementation. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To help determine the proper level of supplementation that works you, gradually increase the number of tablets (maximum 1600 mg/day) and consult with your doctor, until benefits are achieved.


Interactions:

SAM-e should be avoided when taking:

  • St. John’s Wort and MAO Inhibitors, like Marplan, Nardil, Parnate, Manerix

SAM-e should be used with caution and only under a doctor’s supervision when combined with:

  • Other drugs that increase neurotransmitters levels in the body such as Selective Serotonin Reuptake Inhibitors (SSRI’s)

Caution: People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision. If you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before using this product.


Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product.  Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as:

  • Diminished drug effectiveness
  • Reduced supplement effectiveness
  • Impaired drug and/or supplement absorption

FAQs

Can children take SAM-e?

Since SAM-e hasn’t been well studied in children yet, you should not give it to your child without a doctor’s recommendation.

Can I take other drugs or supplements with SAM-e?

Consult your doctor before using SAM-e if you are using any medications. People taking MAO inhibitors for depression, or anyone with bipolar depression, should not take SAM-e. Individuals taking SSRIs should not take SAM-e without a doctor’s supervision.

Can I take SAM-e if I’m pregnant or nursing?

Even though SAM-e is safe under most circumstances, pregnant or nursing women should never take any drug or supplement without consulting a doctor.

How long should I keep taking SAM-e?

SAM-e supplements may be taken on a daily basis. SAM-e can be used daily for the benefits for mood and joint. So you can continue taking SAM-e as long as you are not experiencing any adverse effects and experience results. If you have any concerns or have changes in your medications please consult your doctor.

How long will SAM-e take to work?

Many people report mood improvement in as little as one to two weeks. If after 2 weeks you are not experiencing desired benefits, you may want to try gradually increasing the dose after consulting with your doctor. If you’re taking SAM-e for your joints, you may have to wait up to a month to experience results.

How much SAM-e should I take?

You should start out with 200-400 mg of SAM-e every day. If benefits are not achieved within two weeks, you may require a higher level of supplementation. To determine the proper level of supplementation that works for you, gradually increase the number of tablets (maximum 1600 mg/day) and consult with your doctor until you begin to experience the desired benefits.

How should I take SAM-e?

You should take SAM-e first thing in the morning, at least half an hour before you eat. If this bothers you, you can split your dose and take half before breakfast and half before lunch. For easier swallowing, take with water before and during ingestion. Taking SAM-e before bed may make it more difficult to fall asleep.

What are some dietary sources of SAM-e Complete?

SAM-e is naturally made in most cells of the body and there are no direct SAM-e dietary sources. Increasing your intake of foods containing the amino acid Methionine may help your body increase its SAM-e production. Methionine food sources include: protein based foods such as fish, beef, eggs, and chicken as well as nuts and seeds.

Who should not take SAM-e?

People with bipolar (manic) depression or who are experiencing severe issues with mood, including thoughts of suicide, should not take this or any other product containing SAM-e except under a doctor's supervision. Also, if you are pregnant or nursing, or taking prescription antidepressant medications, consult your doctor before taking SAM-e.

Why is SAM-e so expensive?

The SAM-e ingredient used to make this product – S-adenosylmethionine tosylate disulfate - is a delicate ingredient. It is moisture sensitive and requires careful packaging in foil blister packs to ensure that each tablet is fresh when you take it.

Quality

For 40 years, we have been obsessed with quality at Nature Made®. From ingredient sourcing, to industry-leading manufacturing practices, to our third-party verification approach, we believe it is our responsibility to lead in delivering quality products and a quality consumer experience. For more information, click here.

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