CholestOff® Plus Liquid Softgel

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Nature Made Cholestoff Plus
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  • 100 Softgels

  • Overview
  • Dosage & Interactions
  • Supplement Facts
  • FAQs
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  • CholestOff® Plus is clinically proven to lower cholesterol.

    Maintaining a healthy cholesterol level is an important part of good heart health.  CholestOff® Plus is made with Reducol™, a proprietary blend of plant sterols and stanols (also called phytosterols) that can help lower LDL (“bad”) cholesterol by reducing the absorption of dietary cholesterol into the bloodstream.

    The National Cholesterol Education Program (NCEP) recommends 2000 milligrams of plant sterols and stanols as part of a therapeutic diet to help lower cholesterol. However, most people only consume 200 milligrams through their diet. CholestOff® Plus provides the additional 1800 milligrams of plant sterols and stanols to help meet what the NCEP recommends for cholesterol reduction. Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of Nature Made CholestOff® supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.  

    CholestOff® Plus is made with esterified sterols and stanols instead of free form sterols and stanols used in CholestOff® Original. These esterified sterols and stanols have been clinically studied and show consistent cholesterol-lowering results. Additionally, Nature Made has conducted clinical trials examining the effects of CholestOff Plus on cholesterol. Our studies show that consuming CholestOff Plus in addition to following the NCEP’s Therapeutic Lifestyle Changes (TLC) diet reduced LDL cholesterol levels. CholestOff® Plus is formulated in an easy-to-swallow softgel.

    Nature Made CholestOff® Plus is guaranteed to meet our high quality standards – it is made from carefully selected ingredients under strict manufacturing processes.

    • Colors Derived from Natural Sources – no synthetic dyes
    • No Artificial Flavors
    • No Preservatives
    • No Yeast or Starch
    • Gluten Free

  • Dosage:

    Take two softgels two times daily with a glass of water or other beverage at your largest meals.


    CholestOff® Plus should be used with caution when combined with:

    • Statin drugs

    Caution: Not for use by children or pregnant or lactating women.  Check with your physician before using CholestOff Plus if you are currently using medications to lower your cholesterol.

    Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product.  Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as:

    • Diminished drug effectiveness
    • Reduced supplement effectiveness
    • Impaired drug and/or supplement absorption

  • Ingredients: Plant Sterols/Stanols (Pine Tree), Sunflower Oil Esters, Gelatin, Glycerin, Medium Chain Triglycerides, Soy Lecithin, Water, Colors Added.

    †Sterols/Stanols are esterified with sunflower oil fatty acids.

    As ingredients may change from time to time, please check the label on the bottle.

  • What is CholestOff® Plus?

    Nature Made® CholestOff® Plus, is a dietary supplement containing a proprietary ingredient called Reducol™ (RE-do-call). Reducol™ is a blend of esterified plant sterols and stanols, also called phystosterols. CholestOff® Plus can help lower LDL (“bad”) cholesterol by reducing the absorption of dietary cholesterol into the bloodstream.

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