Sterols and Stanols: An Effective Way
to Manage Cholesterol

Sterols and stanols are plant-based compounds that have been clinically shown to lower cholesterol levels and support a healthy heart.* Sterols and stanols work to prevent the absorption of dietary sources of cholesterol, which in turn helps to lower total and LDL cholesterol levels in the blood. For people who aim to take an active step towards improving their lipid profile, incorporating sterols and stanols in the diet can be a very valuable choice.*

Sterols and Stanols are Recommended by the National Cholesterol Education Program
As an initial step in the cholesterol management process, the National Cholesterol Education Program, as supported by the National Institutes of Health, recommends 2 grams (2000 mg) of plant sterols and stanols per day. In addition to dietary changes to include foods low in saturated fat, trans fat, and dietary cholesterol, the NCEP encourages other Therapeutic Lifestyle Changes (TLC). These lifestyle modifications include increasing your physical activity and managing your body weight. To learn about these recommendations and how best to carry them out, visit the National Institute of Health’s “Your Guide to Lowering Cholesterol with Therapeutic Lifestyle Changes (TLC)” and read more.

Americans Don’t Get Enough Sterols and Stanols from Diet Alone
Although sterols and stanols are naturally found in fruits, vegetables and grains, they occur in very small quantities, which explains why the average Western diet merely provides 150 to 400 mg per day. In fact, to meet the recommended 2000 mg through dietary intake alone, one would have to consume an enormous amount of approximately 55 large bananas or 13 cups of almonds. To that end, choosing a supplement that provides sterols and stanols can be both a convenient and helpful way to achieve results.

Clinical Study Shows CholestOff® Lowers “Bad” Cholesterol Levels
Participants following the National Cholesterol Education Program’s (NCEP) Therapeutic Lifestyle Changes (TLC) Diet experienced a nearly 5 percent reduction in LDL “bad” cholesterol when CholestOff® was added to their daily regimen, according to a study published in the International Journal of Food Sciences and Nutrition. Nature Made CholestOff® Original is a nutritional supplement containing the naturally occurring plant-based sterols and stanols referred to as free (non-esterified) phytosterols. “The FDA has concluded, ‘scientific evidence establishes that including phytosterols in the diet helps to lower blood total and LDL cholesterol levels,’ and this study demonstrates that this dietary supplement formulation of free phytosterols performs this function,” said study co-author, Kevin C. Maki, Ph.D.

The double-blind crossover study showed that consuming CholestOff® daily, containing 1.8 grams of free phytosterols, in conjunction with a healthy diet and exercise program significantly reduced the LDL-cholesterol levels of participants by 4.9 percent after only six weeks of treatment. Belinda H. Jenks, Ph.D., Director of Scientific Affairs & Nutrition Education at Pharmavite LLC., adds, “CholestOff® can easily be added to a cholesterol-lowering regimen without negatively impacting a person’s diet or caloric intake.”

A Supplement for Lowering Cholesterol Levels and Supporting a Healthy Heart*
Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. Nature Made CholestOff® Original Formula and CholestOff® Plus Liquid Softgel products each deliver 1800 mg of sterols and stanols per day when taken as directed, and are a great option for people who are concerned about their cholesterol levels due to their dietary intake of cholesterol. When CholestOff Original and CholestOff Plus Liquid Softgels are paired with one’s diet, it offers a smart strategy for meeting the recommended 2000 mg per day and supporting overall heart health.*

*Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of Nature Made CholestOff® supplies 900 mg of plant sterols and stanols for a daily intake of 1800 mg.