St. John's Wort

Text Size

Nature Made St John's Wort

  • Overview
  • Dosage & Interactions
  • Supplement Facts
  • FAQs
  • Reviews
  • Buy Now
  • Nature Made St. John's Wort Extract may help maintain a healthy emotional balance.


    Nature Made St. John`s Wort Extract has earned a growing reputation as an herb that can help enhance mood. St. John`s Wort Extract comes from the dried flowers of a woody, perennial plant that is sometimes known as Klamath weed. This herb contains numerous compounds including hypericin, flavonoids, phenols and other compounds, which together may be responsible for its mood-enhancing properties.


    • May help enhance mood
    • Natural solution for mental well-being
    • May help maintain a healthy emotional balance

    Nature Made St. John's Wort is guaranteed to meet our high quality standards – it is made from carefully selected ingredients under strict manufacturing processes.


    • Nature Made is the #1 Pharmacist Recommended Brand*
    • No Artificial Flavors
    • No Preservatives
    • No Yeast, No Starch, No Gluten

    *Based on US News & World Report - Pharmacy Times Survey, Nature Made is the #1 Pharmacist Recommended Brand in Eight Segments - Letter Vitamins, Omega-3/Fish Oil, Coenzyme Q10, Flax Seed Oil, , Herbal supplements, Cholesterol Management-Natural, Garlic (tie) and Diabetic Multivitamins (tie).

  • Dosage:

    As an addition to the diet, take two tablets daily with water at mealtimes.


    Interactions:

    The following drug classes should be avoided with St. John’s Wort:


    • Oral Contraceptives:

      St. John’s Wort may interfere with the effectiveness of oral contraceptives. Women taking St. John's Wort and oral contraceptives concurrently should use an additional or alternative form of birth control

    • AntiDepressants:

      St John's Wort in combination with antidepressants can increase the risk of side effects, such as serotonin syndrome. Do not use with antidepressants unless recommended and monitored by a physician or other healthcare professional.

    • Anti-Psychotics:

      St John's Wort in combination with other psychotropic drugs may interfere with the effectiveness of the drug and increase the skin’s sensitivity to light (photosensitivity).

    Use with extreme caution or avoid in patients taking anti-psychotics Potential interactions may occur with the following:


    • Drugs that are metabolized by the cytochrome P450 (CYP3A4) enzyme system in the liver, which may impact drug efficacy. These include:
      • Lipid-lowering drugs (Statins)
      • Oral hypoglycemic drugs (Metformin) or other drugs used to control blood sugar
      • Blood pressure lowering drugs (such as Calcium Channel Blockers)
      • Arthritis medications (NSAIDS, COX -2 Inhibitors)
      • Anti-anxiety drugs (Benzodiazepines)
      • Narcotic analgesics (Opioids)
    • Drugs that increase the skin’s sensitivity to light (photosensitivity)
    • St. John’s Wort may have an additive effect with other photosensitizing drugs, such as Antibiotics and Anti-psychotic drugs

    Limit the exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals. Discontinue use in the event of a rash.


    Caution: If you are pregnant or nursing, consult a health professional before taking this product.  There is a possibility St. John's Wort may interfere with some prescription drugs.  Consult with your physician or pharmacist as needed.  Limit the exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals.  Discontinue use in the event of a rash.


    Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product. Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as:


    • Diminished drug effectiveness
    • Reduced supplement effectiveness
    • Impaired drug and/or supplement absorption


  • OTHER INGREDIENTS: Cellulose Gel, Croscarmellose Sodium, Maltodextrin, Sodium Starch Glycolate, Polyvinyl Alcohol, Silicon Dioxide, Polyethylene Glycol, Magnesium Stearate, Talc, Color Added, Yellow 5 Lake, Triethyl Citrate, Polysorbate 80, Yellow 6 Lake, Blue 2 Lake, Stearic Acid.


    As ingredients may change from time to time, please check the label on the bottle.

  • Are there any side effects to be aware of when taking St. John's Wort?

    The side effects of St. John’s Wort include possible photosensitization at high dosages, especially in fair-skinned individuals. In addition, drugs that are metabolized by the cytochrome P450 (CYP3A4) enzyme system in the liver, which may impact effectiveness of the drug. There may be mild gastrointestinal irritation, allergic reactions, fatigue, and restlessness. Also, St. John's Wort may interfere with the effectiveness of oral contraceptives. Women taking St. John's Wort and oral contraceptives concurrently should use an additional or alternative form of birth control.

    Do Nature Made® Herbs products contain artificial flavors/colors?

    Nature Made® and Nature Made® Herbs product lines are made to strict quality standards of purity, potency and release. Most all products are produced without artificial colors or preservatives. The few products that do contain artificial colors will state this in the ingredient listing on the label.

    How long will it take before I feel positive results from taking St. John's Wort?

    St. John’s Wort may help enhance mood. It may take up to 2 months before any results are noticed in some individuals

    I’m using an antidepressant and want to switch to St. John’s Wort. How should I do this?

    If an antidepressant is being used we suggest you speak with a physician prior to switching to this herb.

    Is St. John's Wort a standardized herb?

    Yes. St. John’s Wort is standardized to 0.3% hypericin, when tested by UV.

  • St Johns Wort 3.7 5 3 3
    using this product for 10 years This is my favorite brand of St JohnsWort. Its the only one that I've found that is time release. its effective without making me feel jittery like other more expensive brands. very HAPPY with it. :-) May 5, 2013
    No significant changes The solid "caplets" are more convenient, easier to swallow, and less susceptible to tampering than the old capsules. Very pleased with new formulation. March 26, 2012
    This product has changed to a solid pill form from a gel cap with herbs inside. The product does not work as the gel pill form works. It is not just St John's Wort since more ingredients are needed to make a whole pill. I would gladly pay more to get the original gel cap back. November 26, 2011
    1-3 of 3
  • or

    Find in Store

Coupon Center

Save on St. John's Wort

See all coupons


Related products

Nature Made SAM-e Complete 200mg SAM-e Complete 200 mg
Nature Made SAM-e Complete 400 mg SAM-e Complete 400 mg
Nature Made Super Strength Omega-3 Super Strength Omega-3 EPA