• Nature Made St. John's Wort 450 mg
  • Nature Made St. John's Wort 450 mg

St. John's Wort 450 mg

Capsules

Nature Made St. John's Wort Extract may help support a healthy mood.

  • Nature Made is the #1 Pharmacist Recommended Mood Health Supplement Brand*
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Product Details

St. John's Wort extract comes from the dried flowers of a woody, aromatic perennial plant that blooms yellow flowers. This herb contains numerous compounds including hypericin, flavonoids, phenols and other compounds. Scientists have found that these naturally occurring chemicals may be involved in supporting a healthy mood.

Nature Made St. John's Wort is guaranteed to meet our high quality standards – it is made from carefully selected ingredients under strict manufacturing processes.

  • Nature Made is the #1 Pharmacist Recommended Mood Health Supplement Brand*
  • No Artificial Flavors
  • No Color Added
  • No Preservatives
  • No Yeast or Starch
  • Gluten Free

Available Sizes: 40 Count

*Based on US News & World Report - Pharmacy Times Survey of pharmacist recommending in this category

Nature Made When to Take Your Vitamins

Dosage and Interactions

Dosage:

For Adults, take two tablets daily with water at mealtimes.


Interactions:

The following drug classes should be avoided with St. John’s Wort:

  • Oral Contraceptives:

    St. John’s Wort may interfere with the effectiveness of oral contraceptives. Women taking St. John's Wort and oral contraceptives concurrently should use an additional or alternative form of birth control

  • Antidepressants:

    St John's Wort in combination with antidepressants can increase the risk of side effects, such as serotonin syndrome. Do not use with antidepressants unless recommended and monitored by a physician or other healthcare professional.

  • Anti-Psychotics:

    St John's Wort in combination with other psychotropic drugs may interfere with the effectiveness of the drug and increase the skin’s sensitivity to light (photosensitivity).

Use with extreme caution or avoid in patients taking anti-psychotics Potential interactions may occur with the following:

  • Drugs that are metabolized by the cytochrome P450 (CYP3A4) enzyme system in the liver, which may impact drug efficacy. These include:
    • Lipid-lowering drugs (Statins)
    • Oral hypoglycemic drugs (Metformin) or other drugs used to control blood sugar
    • Blood pressure lowering drugs (such as Calcium Channel Blockers)
    • Arthritis medications (NSAIDS, COX -2 Inhibitors)
    • Anti-anxiety drugs (Benzodiazepines)
    • Narcotic analgesics (Opioids)
  • Drugs that increase the skin’s sensitivity to light (photosensitivity)
  • St. John’s Wort may have an additive effect with other photosensitizing drugs, such as Antibiotics and Anti-psychotic drugs

Limit the exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals. Discontinue use in the event of a rash.

Caution: Not for use by children. If you are pregnant or nursing, consult a health professional before taking this product. There is a possibility St. John's Wort may interact or interfere with some prescription drugs, including blood thinners, oral contraceptives and antidepressants. Consult with your physician or pharmacist before using this product if you are taking any prescription drug, and visit NatureMade.com for additional contraindiction information. Side effects, such as rash, dizziness or nausea, may occur. St. John’s Wort is a stimulant and may worsen feelings of anxiety in some people. Psychosis is a rare but possible side effect of taking St. John’s Wort, particularly in people who have or are at risk for mental health disorders, including bipolar disorder. Limit exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals. Discontinue use and consult a health care provider if you experience any side effects.

Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product. Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as:

  • Diminished drug effectiveness
  • Reduced supplement effectiveness
  • Impaired drug and/or supplement absorption

FAQs

Are there any side effects to be aware of when taking St. John's Wort?

The side effects of St. John’s Wort include possible photosensitization at high dosages, especially in fair-skinned individuals. In addition, drugs that are metabolized by the cytochrome P450 (CYP3A4) enzyme system in the liver, which may impact effectiveness of the drug. There may be mild gastrointestinal irritation, allergic reactions, fatigue, and restlessness. Also, St. John's Wort may interfere with the effectiveness of oral contraceptives. Women taking St. John's Wort and oral contraceptives concurrently should use an additional or alternative form of birth control.

Do Nature Made® herbal supplements contain artificial flavors/colors?

Nature Made herbal supplements are made to strict quality standards of purity, potency and release. Most products are produced without artificial colors or flavors. The few products that do contain artificial colors will state this in the ingredient listing on the label.

How long will it take before I feel positive results from taking St. John's Wort?

St. John’s Wort may help support a healthy mood.† It may take up to 2 months before any results are noticed in some individuals.

I’m using an antidepressant and want to switch to St. John’s Wort. How should I do this?

If an antidepressant is being used we suggest you speak with a physician prior to taking this herb.

Is St. John's Wort a standardized herb?

Yes. St. John’s Wort is standardized to 0.3% hypericin, when tested by UV.

Quality

For 40 years, we have been obsessed with quality at Nature Made®. From ingredient sourcing, to industry-leading manufacturing practices, to our third-party verification approach, we believe it is our responsibility to lead in delivering quality products and a quality consumer experience. For more information, click here.
  • Nature Made® is the #1 Pharmacist Recommended Brand in Nine Categories, based on US News & World Report - Pharmacy Times Survey. – Nature Made has been recognized in the Letter Vitamins, Omega-3/Fish Oil, Coenzyme Q10, Flax Seed Oil, Herbal Supplements, Cholesterol Management-Natural, Garlic, Diabetic Multivitamins and Mood Health Supplements categories.