For Adults, take two tablets daily with water at mealtimes.
The following drug classes should be avoided with St. John’s Wort:
Use with extreme caution or avoid in patients taking anti-psychotics Potential interactions may occur with the following:
- Drugs that are metabolized by the cytochrome P450 (CYP3A4) enzyme system in the liver, which may impact drug efficacy. These include:
- Lipid-lowering drugs (Statins)
- Oral hypoglycemic drugs (Metformin) or other drugs used to control blood sugar
- Blood pressure lowering drugs (such as Calcium Channel Blockers)
- Arthritis medications (NSAIDS, COX -2 Inhibitors)
- Anti-anxiety drugs (Benzodiazepines)
- Narcotic analgesics (Opioids)
- Drugs that increase the skin’s sensitivity to light (photosensitivity)
- St. John’s Wort may have an additive effect with other photosensitizing drugs, such as Antibiotics and Anti-psychotic drugs
Limit the exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals. Discontinue use in the event of a rash.
Caution: Not for use by children. If you are pregnant or nursing, consult a health professional before taking this product. There is a possibility St. John's Wort may interact or interfere with some prescription drugs, including blood thinners, oral contraceptives and antidepressants. Consult with your physician or pharmacist before using this product if you are taking any prescription drug, and visit NatureMade.com for additional contraindiction information. Side effects, such as rash, dizziness or nausea, may occur. St. John’s Wort is a stimulant and may worsen feelings of anxiety in some people. Psychosis is a rare but possible side effect of taking St. John’s Wort, particularly in people who have or are at risk for mental health disorders, including bipolar disorder. Limit exposure to the sun as St. John's Wort may cause increased photosensitivity in fair skinned individuals. Discontinue use and consult a health care provider if you experience any side effects.
Given that no two people are alike, if you are taking any medications you should be aware that potential drug-nutrient interactions may occur and are encouraged to consult a health care professional before using this product. Combining certain prescription drugs and dietary supplements can lead to undesirable effects such as:
- Diminished drug effectiveness
- Reduced supplement effectiveness
- Impaired drug and/or supplement absorption